SET8 Methyltransferase Inhibitor 96 by Cayman Chemical
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Product details
| Management number | 210990470 | Release Date | 2026/04/04 | List Price | US$36.00 | Model Number | 210990470 | ||
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SET8, a methyltransferase, specifically mono-methylates histone H4 at lysine 20 (H4K20), a process crucial for chromatin structure and gene expression. SET8, included in the kit, transfers a methyl group from S-adenosylmethionine (SAM) to the H4K20 peptide, generating S-adenosylhomocysteine. This is then rapidly converted to urate and hydrogen peroxide (H2O2) using the provided enzyme mix. The produced H2O2 reacts with ADHP to create resorufin, a highly fluorescent compound (excitation 530-540 nm; emission 585-595 nm).
| Item Form | Powder |
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| Brand Name | Cayman Chemical |
| Manufacturer | Cayman Chemical |
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